Heat Transfer and Residence Time Distribution in Plug Flow Continuous Oscillatory Baffled Crystallizers

Heat transfer coefficients in a continuous oscillatory baffled crystallizer (COBC) with nominal internal diameter of 15 mm have been determined as function flow and conditions typically used under processing conditions. Residence time distribution measurements show near-plug high Peclet numbers on the order 100–1000 s, although there was significant oscillation damping longer COBC setups. Very rapid heat found typical conditions, overall 100 s W m–2 K–1. Furthermore, poor mixing cooling jacket observed when lower rates were implemented an attempt to decrease rate achieve more gradual temperature profile along length. Utilizing experimentally coefficients, theoretical case study is presented investigate effects supersaturation profiles highlight potential fouling issues during plug crystallization.